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European food safety regulators have since labeled titanium dioxide as no longer safe for human consumption, due to its potential toxicity. 

Description:

The most significant uncertainty identified by the EU experts was the concern that TiO₂ particles may have genotoxic effects. Genotoxicity refers to the ability of a chemical to directly damage genetic material within a cell (DNA), which may lead to cancer in certain situations. Although the experts did not conclude that TiO₂ particles in E171 are genotoxic, they could not rule out the concern that they might be.

North America

At present, the equipment and manufacturing process of domestic manufacturers of polyvinyl butyral are constantly getting closer to those abroad. For example, the wonderful use of polyvinyl butyral (PVB) has occurred in the printing industry and ceramic industry. Therefore, the domestic application of polyvinyl butyral (PVB) has an obvious upward trend in recent years.

For example, in the glass industry, it is because polyvinyl butyral (PVB) has good low-temperature impact strength, windability, light transmittance, light resistance, weather resistance, sound insulation, UV insulation and other properties, so that once the laminated glass is sealed together, the glass sandwich (i.e. laminated material) will appear as a whole and look like ordinary glass. For example, in the porcelain industry, polyvinyl butyral is made into a film and used for printing paper film of ceramic (or enamel) products. First, it reduces the original glue small paper Decal process, reduces the production cycle and production cost, and second, it makes its ceramic (or enamel) patterns bright in color and smooth in texture.

With the rapid development of science and technology in recent years, more and more industries have found the characteristics of polyvinyl butyral (PVB): high strength, high toughness, fatigue resistance, corrosion resistance and so on. Compared with traditional materials, polyvinyl butyral (PVB) is more and more widely used because of its larger development space and wider application fields!

Application field of polyvinyl butyral -- safety glass

The membrane made of polyvinyl butyral (PVB) is a special product used to manufacture safety glass and bulletproof glass. Safety glass is a special glass made of a layer of PVB diaphragm sandwiched between two layers of ordinary glass. It has good low-temperature impact strength, windability, light transmittance, light resistance, weather resistance, sound insulation, ultraviolet insulation and other properties. When subjected to strong external impact, PVB diaphragm can absorb impact energy, so that the glass will not break or prevent debris from hurting people. Moreover, the safety glass added with PVB diaphragm has the characteristics of high transparency, water resistance and aging resistance, and can be used in the environment of - 60 ℃. In addition, it can also be used as transparent material to replace plexiglass.

Application field of polyvinyl butyral -- ceramic film flower paper 

Among the raw materials for coating production, titanium dioxide is more ideal, followed by lithopone. The covering power of lithopone is only that of titanium dioxide, and the price of lithopone is much lower than that of titanium dioxide, so lithopone still occupies a large market share.

In vitro, in the hemocytes of the marine mussel Mytilus hemocytes, suspension of TiO₂ NPs (Degussa P25, 10 μg/ml) stimulated immune and inflammatory responses, such as lysozyme release, oxidative burst and nitric oxide production. Vevers and Jha demonstrated the intrinsic genotoxic and cytotoxic potential of TiO₂ NPs on a fish-cell line derived from rainbow-trout gonadal tissue (RTG-2 cells) after 24 h of exposure to 50 μg/ml. Reeves et al. demonstrated a significant increase in the level of oxidative DNA damage in goldfish cells, and suggested that damage could not repaired by DNA repair mechanisms. Another suggestion from the mentioned study was that hydroxyl radicals are generated also in the absence of UV light. It has been shown that fish cells are generally more susceptible to toxic/oxidative injury than mammalian cells.

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