For people in occupational settings that increase the risk of titanium dioxide exposure, taking protective measures is helpful. This may include wearing protective equipment, such as respirators, and using ventilation systems.
After conducting a review of all the relevant available scientific evidence, EFSA concluded that a concern for genotoxicity of TiO2 particles cannot be ruled out. Based on this concern, EFSA’s experts no longer consider titanium dioxide safe when used as a food additive. This means that an Acceptable Daily Intake (ADI ) cannot be established for E171.