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- These manufacturers not only contribute to the scientific advancements but also drive economic growth. They create jobs, stimulate local economies, and foster technological innovations. The 1317-80-2% manufacturers cater to a diverse range of industries, from pharmaceuticals and healthcare to agriculture and industrial chemicals. The compound's unique properties make it a crucial ingredient in the formulation of numerous products, highlighting the extensive reach of these manufacturers.
- Titanium dioxide, commonly known as TIO2, is a versatile and essential compound widely used in various industries. This white pigment is renowned for its high refractive index and excellent UV protection properties, making it an ideal choice for numerous applications. As a leading TIO2 products supplier, we understand the importance of providing high-quality titanium dioxide to meet the diverse needs of our clients.
- Chemical building coatings are essential for protecting structures from the harsh elements and enhancing their aesthetics. These coatings are specially formulated to provide a protective barrier against weathering, corrosion, and other environmental factors that can degrade building materials over time.


Yet another study, this one published in 2006 by the International Agency for Research on Cancer said there was insufficient evidence to conclude that titanium dioxide causes cancer. However, the study also categorized the ingredient as a potential human carcinogen.

Titanium Dioxide is one of the two members of the elite sunscreen group called physical sunscreens (or inorganic sunscreens if you’re a science geek and want to be precise).
Titanium dioxide is the most widely used whitening pigment in the world and has been linked to adverse health effects, particularly genotoxicity and intestinal inflammation. It is applied as food coloring and a whitening agent to a wide variety of foods, including chewing gum, cakes, candies, breads and ice cream.
Titanium dioxide is a widely used substance in various industries due to its versatility and unique properties. As a result, there are numerous manufacturers of titanium dioxide around the world, catering to the different needs of their customers.
Titanium dioxide mainly comes from the earth’s crust, where it’s actually the ninth most common element. When processed, it becomes a fine powder with a vibrant white pigment.

In the same year (2019), the Netherlands Food and Consumer Product Safety Authority (NVWA) also delivered an opinion on possible health effects of food additive titanium dioxide, which highlighted the importance of examining immunotoxicological effects in addition to potential reprotoxicological effects.
It’s true that titanium dioxide does not rank as high for UVA protection as zinc oxide, it ends up being a small difference (think about it like being 10 years old versus 10 years and 3 months old). This is not easily understood in terms of other factors affecting how sunscreen actives perform (such as the base formula), so many, including some dermatologists, assume that zinc oxide is superior to titanium dioxide for UVA protection. When carefully formulated, titanium dioxide provides excellent UVA protection. Its UVA protection peak is lower than that of zinc oxide, but both continue to provide protection throughout the UVA range for the same amount of time.
Lithopone B301, Lithopone B311 powder’s 2 main components:
ZnSO4 – BaS ➔ BaSO4*ZnS
How we’re exposed to an ingredient matters greatly in terms of our long-term health.
Research shows that inhaling titanium dioxide particles in significant quantities over time can cause adverse health outcomes. Unless you work in an industrial setting, inhaling substantial amounts of titanium dioxide is highly unlikely.
In an early study Jani et al. administred rutile TiO2 (500 nm) as a 0.1 ml of 2.5 % w/v suspension (12.5 mg/kg BW) to female Sprague Dawley rats, by oral gavage daily for 10 days and detected presence of particles in all the major gut associated lymphoid tissue as well as in distant organs such as the liver, spleen, lung and peritoneal tissue, but not in heart and kidney. The distribution and toxicity of nano- (25 nm, 80 nm) and submicron-sized (155 nm) TiO2 particles were evaluated in mice administered a large, single, oral dosing (5 g/kg BW) by gavage. In the animals that were sacrificed two weeks later, ICP-MS analysis showed that the particles were retained mainly in liver, spleen, kidney, and lung tissues, indicating that they can be transported to other tissues and organs after uptake by the gastrointestinal tract. Interestingly, although an extremely high dose was administrated, no acute toxicity was observed. In groups exposed to 80 nm and 155 nm particles, histopathological changes were observed in the liver, kidney and in the brain. The biochemical serum parameters also indicated liver, kidney and cardiovascular damage and were higher in mice treated with nano-sized (25 or 80 nm) TiO2 compared to submicron-sized (155 nm) TiO2. However, the main weaknesses of this study are the use of extremely high single dose and insufficient characterisation of the particles.



However, humans are not exposed to E171 in drinking water at any significant quantity over a long duration, so this potential effect is irrelevant to the human experience. It’s important to understand that a potential hazard is not the same thing as an actual risk.
TiO2 is also used in oral pharmaceutical formulations, and the Pharmaceutical Excipients handbook considers nano-sized TiO2 a non-irritant and non-toxic excipient. Despite the fact that TiO2 submicron- and nano-sized particles are widely used as food and pharmaceutical additives, information on their toxicity and distribution upon oral exposure is very limited.