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Zinc Oxide
- In addition to its uses in traditional industries, titanium dioxide is also finding new applications in emerging fields such as solar energy and water treatment. In solar cells, titanium dioxide is used as a photocatalyst to convert sunlight into electricity. In water treatment, it is used to remove impurities and disinfect water, making it suitable for drinking and industrial use.
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Colour Characteristics
The Scientific Committee on Consumer Safety (SCCS) warns against sprayable products and powders that may expose users’ lungs to titanium dioxide through inhalation (10).


lithopone supplier 30% applied in masterbatch has maximum purity, good opacity and reasonable light fastness.
The first study addressing the experimental convergence between in vitro spiking neurons and spiking memristors was attempted in 2013 (Gater et al., 2013). A few years later, Gupta et al. (2016) used TiO2 memristors to compress information on biological neural spikes recorded in real time. In these in vitro studies electrical communication with biological cells, as well as their incubation, was investigated using multielectrode arrays (MEAs). Alternatively, TiO2 thin films may serve as an interface material in various biohybrid devices. The bio- and neurocompatibility of a TiO2 film has been demonstrated in terms of its excellent adsorption of polylysine and primary neuronal cultures, high vitality, and electrophysiological activity (Roncador et al., 2017). Thus, TiO2 can be implemented as a nanobiointerface coating and integrated with memristive electronics either as a planar configuration of memristors and electrodes (Illarionov et al., 2019) or as a functionalization of MEAs to provide good cell adhesion and signal transmission. The known examples are electrolyte/TiO2/Si(p-type) capacitors (Schoen and Fromherz, 2008) or capacitive TiO2/Al electrodes (Serb et al., 2020). As a demonstration of the state of the art, an attempt at memristive interlinking between the brain and brain-inspired devices has been recently reported (Serb et al., 2020). The long-term potentiation and depression of TiO2-based memristive synapses have been demonstrated in relation to the neuronal firing rates of biologically active cells. Further advancement in this area is expected to result in scalable on-node processors for brain–chip interfaces (Gupta et al., 2016). As of 2017, the state of the art of, and perspectives on, coupling between the resistive switching devices and biological neurons have been reviewed (Chiolerio et al., 2017).
It is a national high-tech enterprise, a national top 500 chemical enterprise, and the largest titanium dioxide exporter in China. The main products are TiO2, zirconium products, sulfuric acid and sulfate. Among them, titanium dioxide has reached 120,000 tons, and its export volume has ranked first in the country for three consecutive years. The annual production capacity of the main titanium dioxide is 600,000 tons, ranking first in Asia and fourth in the world.
The inception and evolution of lithopone can be traced back through various industries and diverse applications. Revered for its robust hiding power, this white pigment, also called sulfide of zinc white, has been an invaluable asset to industries requiring a durable and reliable white pigment. Lithopone was an economical and functional solution as an alternative to lead carbonate, which is prone to change, and zinc oxide, known for its brittleness.
The main concern with nanoparticles is that they are so tiny that they are absorbed into the skin more than we want them (ideally sunscreen should remain on the surface of the skin). Once absorbed they might form unwanted complexes with proteins and they might promote the formation of evil free radicals. But do not panic, these are concerns under investigation. A 2009 review article about the safety of nanoparticles summarizes this, to date, in-vivo and in-vitro studies have not demonstrated percutaneous penetration of nanosized particles in titanium dioxide and zinc oxide sunscreens. The English translation is, so far it looks like sunscreens with nanoparticles do stay on the surface of the skin where they should be.

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That being said, most experts tell us that these potential health risks shouldn’t trouble us, because titanium dioxide has been used in the market for decades, and no adverse reactions have been reported by users. The bottom line is that when used correctly, titanium dioxide should be a safe ingredient that’s safe for all skin types, every day
The author thanks Marco Leona, Scientist-in-Charge of the Department of Scientific Research at the Metropolitan Museum of Art for conducting fluorescence spectrometry on Wheel of Fortune and a valuable discussion of the research, as well as Silvia Centeno, Research Scientist at the Metropolitan Museum of Art, who performed Raman analysis on the watercolors and also contributed her insight. The phenomenon of the phosphorescing lithopone was originally discovered during the author's fellowship in the Sherman Fairchild Center for the Conservation of Works on Paper, funded by the Andrew W. Mellon Foundation. The author thanks all her colleagues for their ideas and support during the research of this paper, and special thanks to Rachel Mustalish for her assistance in editing this work.
In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”
