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Should I be worried about the use of titanium dioxide in my toothpaste?
Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”
4. Should I stop eating products that contain TiO2?
Thanks to its rheological and optical properties, Lithopone offers both technical and economic advantages wherever organic and inorganic binder systems require a relatively high pigmentation for specific applications.
In a review published in 2022 in the journal Archives of Toxicology, researchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivo, ex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”
There is some concern regarding skin and intestinal absorption of titanium dioxide nanoparticles, which are less than 100 nm in diameter.
JECFA also evaluated estimates of dietary exposure to titanium dioxide, estimating the maximum 95th percentile of exposure to be 10 mg/kg BW per day. Overall, considering the low oral absorption of titanium dioxide as a food additive, the committee reaffirmed the ADI “not specified” that was established at the 13th meeting.

In the meantime, some big manufacturers boosted their product pricing to better their margins, such as Venator, which increased its titanium dioxide prices by roughly 160 USD /MT for the third quarter of 2021 in the North America region. Overall, prices for Anatase grade in the United States hovered about 3485 USD /MT through the end of June.
It adds a bright white color to coffee creamers, baked goods, chewing gums, hard-shell candies, puddings, frostings, dressings, and sauces. But the nanoparticles found in “food-grade” titanium dioxide may accumulate in the body and cause DNA damage—which is one way chemicals cause cancer and other health problems.

The alarming fact of this study is that it was only conducted for 100 days, I have been wearing makeup daily for at least the last fifteen years & would have eaten kilo's of lipstick in my life time - what effects has this had on my system & health??
Reacting to the report, France’s ministers of health, agriculture and economy instructed the country’s food health and safety agency, Anses, to investigate whether the additive poses a risk for human health.
The study was said to be prompted by “growing concerns that daily oral… Intake is associated with an increased risk of chronic intestinal inflammation and carcinogenesis”, or cancer formation”.
At our manufacturing facility, we are committed to sustainability and environmental responsibility. We take great care to ensure that our production processes are as environmentally friendly as possible, and we are constantly looking for ways to reduce our carbon footprint. By choosing our nano titanium dioxide products, customers can be confident that they are supporting a company that is dedicated to preserving the planet for future generations.
Reason for listing: CNNC Huayuan Titanium Dioxide Co., Ltd., a well-known brand of titanium dioxide factory, started in 1989, specializing in the research and development, production, sales and service of titanium dioxide products. One of the titanium dioxide enterprises producing more than 10,000 tons.
Yesterday, some parts of the domestic rutile, anatase titanium dioxide new single price to maintain stability, titanium dioxide factory normal, more delivery of early orders, spot shipping pressure is small; And the buyer just needed to buy a few days ago. Downstream manufacturers are currently watching the latest execution price.The key factors affecting the current market price change1. Inventory: Low inventory of mainstream producers, mainly delivery of pre-contract orders, is expected today's spot inventory is still low, mainstream factories before the holiday spot tension.2. Mentality: the buyer has to prepare goods in advance, and the new order price is slightly less willing to purchase in bulk; Sellers due to the lack of inventory, manufacturers have no willingness to reduce the price of sales in the market of new orders just need to buy more.Trend: The load of titanium dioxide enterprises is stable, the willingness to ship at low prices is not strong, and the downstream buyer's early orders continue to digest, and the acceptance of the purchase before the holiday is acceptable. It is expected that the market of titanium dioxide just needs to be closed today, and it is concerned about the new execution price of the mainstream factory.
Lithopone was discovered in the 1870s by DuPont. It was manufactured by Krebs Pigments and Chemical Company and other companies.[2] The material came in different seals, which varied in the content of zinc sulfide. Gold seal and Bronze seals contain 40-50% zinc sulfide, offering more hiding power and strength.[3] Although its popularity peaked around 1920, approximately 223,352 tons were produced in 1990. It is mainly used in paints, putty, and in plastics.[1]
Respiratory Exposure
Ultimately, most experts advise moderation, as titanium dioxide is typically found in processed foods that come with their own health risks.
Hebei Caixin Material Technology Co., LTD., formerly established in 2005, is located in the core of Beijing-Tianjin-Hebei City cluster, close to Tianjin Port, the largest port in the north, with developed transportation and outstanding people. After the continuous efforts of Caiqing people, has accumulated assets for the company of nearly 200 million, nearly 1,000 employees, Caiqing technology has become the pigment titanium dioxide research and development, production, sales and import and export trade in one of the large company, we integrate industry resources, to provide personalized customized services for global customers. We adhere to the market-oriented, good faith as the principle, is committed to open up a diversified international market, for the world customers to provide quality products, efficient service, is our unremitting pursuit. We sincerely invite customers from all over the world to visit our company.


The toxicity of P25TiO2NPs under UV radiation could be even higher when combined with other usual components of sunscreens Indeed, Soler de la Vega et al. advise that combination with parabens increases the toxicity of the final cosmetic mixture [53].
New Safety Rulings & Regulations
With the rise of nanotechnology, research in recent years has also shown the dangers of titanium dioxide (TiO2) nanoparticles, and their genotoxicity, which refers to a chemical agent’s ability to harm or damage DNA in cells, thus potentially causing cancer.
If you want to avoid titanium dioxide, Stoiber and Faber urge consumers to try and avoid processed foods as best as you can.