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HPMC CAS : No. 004-65-3
The Joint FAO/WHO Expert Committee on Food Additives (JECFA, 1990) assessed the compound together with six other cellulose derivatives and allocated a group acceptable daily intake (ADI) of ‘not specified’. The Scientific Committee for Food (SCF, 1994, 1999) who assessed five closely related cellulose derivatives, also allocated a group ADI of ‘not specified’. The most recent evaluation of cellulose and cellulose derivatives, including HPMC for their use as food additives was done in 2018 by the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) (EFSA ANS Panel, 2018), which concluded that there was no need to set a numerical ADI.
The present assessment is based on data submitted by the applicant in the form of a technical dossier5 in support of the authorisation request for the use of HPMC as a feed additive.
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