micore 300 mineral fiber board

≤0.3

For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

Hiding power

≤14

The lack of clear regulations and controls explains that P25TiO₂NPs are still found in many of the commercialized sunscreens in the market. Some of them are coated to reduce the photoactivity of the anatase form, which is known to be responsible for tissue damage, but not enough studies were made on these coated forms. The anatase photoactivity could trigger the production of reactive oxygen species (ROS) generation, as it was stated before. The ROS are chemically reactive species containing oxygen, such as peroxides, superoxide, hydroxyl radical, and singlet oxygen. They are regularly produced in the biological milieu and counterbalanced by physiological antioxidant defense mechanisms. However, an abrupt increase of ROS may result in non-reversible damage to the skin cells. The effects of coated and uncoated P25TiO₂NPs need therefore to be studied, and articles on this topic present different conclusions. [11], [12], [13] Recent literature on this topic found that TiO₂NPs inhalation provokes serious genotoxicity and DNA damage [14], [15], [16], [17]. On the other hand, some studies in rats have reported no significant harm to genetic material [18], [19], [20], [21], [22].

Not everyone agrees, though. The European Commission banned titanium dioxide as a food additive in the European Union in 2022.

In recent years, titanium dioxide (TiO2) has gained immense popularity across various industries due to its excellent properties, such as high opacity, brightness, and ultraviolet light absorption. As a result, the demand for titanium dioxide has increased significantly, prompting a surge in the number of manufacturers hoping to capitalize on this booming market. While quality remains a priority, cost-effectiveness has emerged as a crucial factor for consumers, leading to a growing interest in cheap titanium dioxide manufacturers.

3. What is EFSA saying in its 2021 opinion on the safety of titanium dioxide as a food additive?

3. Solubility: insoluble in water.

TiO2 powder is also widely used in the cosmetics industry, where it is used as a whitening agent in skincare products, sunscreen, and makeup. TiO2 powder suppliers work closely with cosmetic manufacturers to ensure that they have a reliable and high-quality supply of TiO2 powder to meet the demands of their consumers.

In the same year (2019), the Netherlands Food and Consumer Product Safety Authority (NVWA) also delivered an opinion on possible health effects of food additive titanium dioxide, which highlighted the importance of examining immunotoxicological effects in addition to potential reprotoxicological effects.